Published by HESA, the register is the most comprehensive dataset of its kind, providing the first open and auditable record of spinout activity across the UK青瓜视频檚 higher education sector. It captures all spinout companies established by UK universities between 2012/13 and 2023/24, offering a robust measure of how effectively research is being translated into commercial ventures.

The University of Manchester青瓜视频檚 performance reflects more than a decade of sustained effort to support its researchers in building successful, impactful businesses from world-class academic work. Driven by The University of Manchester Innovation Factory, 122 spinout companies were established during the period covered by the register, in fields ranging from advanced materials and biotech to environmental innovation.

The Innovation Factory plays a central role in this success. As the University青瓜视频檚 Technology Transfer Office (TTO), the Innovation Factory is responsible for the commercialisation of the University青瓜视频檚 research. This includes supporting the creation and development of spinout companies based on ideas and discoveries generated by the University青瓜视频檚 academics.

Dr Catherine Headley, CEO of the Innovation Factory, said: 青瓜视频淭his is a fantastic recognition of the strength of our innovation community in Manchester. It shows not just how many spinouts we青瓜视频檙e helping to launch, but the real value of the support we offer to researchers with great ideas. 

"We青瓜视频檙e proud to see so many of those ideas becoming successful businesses, and we青瓜视频檙e committed to helping even more of them make that journey. In doing so, we青瓜视频檙e building on Manchester青瓜视频檚 long history of innovation and helping to secure the city青瓜视频檚 future as a global centre for discovery and enterprise.青瓜视频�

The Innovation Factory provides a full spectrum of technology transfer services, including early-stage evaluation, intellectual property management, licensing, company formation and investor support. It works closely with academic teams, industry partners and investors to ensure that ideas with commercial potential receive the guidance and support they need to succeed.

The HESA Spinout Register has been developed in partnership with Jisc, Research England and the University Commercialisation and Innovation Policy Evidence Unit at the University of Cambridge. It is based on validated institutional returns to the Higher Education Business and Community Interaction (HE-BCI) survey and represents the first national resource of its kind.

The University of Manchester青瓜视频檚 position in the register highlights its commitment to delivering impact through innovation and its leadership in turning research into economic and societal value.

For more information, visit the Innovation Factory .

Catherine steps into the role full-time, having served as Interim CEO over the past year, while also fulfilling her responsibilities as Director of Business Engagement and Knowledge Exchange at The University of Manchester. With a wealth of experience in working with businesses, technology transfer and innovation, she brings a deep commitment to advancing UoMIF青瓜视频檚 mission of identifying and commercialising groundbreaking research to drive social, environmental and economic impact. 

Catherine will be succeeded in her previous role as Director of Business Engagement and Knowledge Exchange by Dr Louise Bates, who joins from her position as Head of Strategic Partnerships at The University of Manchester.

青瓜视频淚 am thrilled to take on this role at such an exciting time for the Innovation Factory,青瓜视频� said Catherine. 青瓜视频淢anchester has a proud and established legacy of pioneering innovation that shapes the world and I am eager to build on that tradition. My goal is to strengthen our partnerships, empower our academics, inventors and researchers, and accelerate the journey from discovery to real-world solutions that benefit society and bolster the UK青瓜视频檚 position as a global leader in innovation.青瓜视频�

The appointment comes at a time when technology transfer offices (TTOs) across the UK are increasingly recognised for their economic contributions. 

A 2023 report highlighted that university spinouts in the UK employ tens of thousands and generate billions in revenue annually, underscoring the critical role of organisations like UoMIF in fostering innovation ecosystems. UoMIF plays a critical role in supporting growth in the region through its spinouts and innovation, and is now perfectly placed to grow and increase the environmental, societal and economic impact that it contributes.

Over the past several years, UoMIF established itself as a vital bridge between academic research and commercial application, supporting the University青瓜视频檚 ambition to create impact through translation of world-class research. Catherine aims to build on this foundation, driving UoMIF towards ambitious goals while reinforcing Manchester青瓜视频檚 historic role as a hub of technological advancement.

Professor Duncan Ivison, President and Vice-Chancellor of The University of Manchester, welcomed the appointment, saying: 青瓜视频淚青瓜视频檓 delighted Catherine is stepping into the role of CEO at the Innovation Factory. Her leadership, creativity, and commitment to bringing our research to life exemplify exactly what we're about as a University. 

"Her appointment will help us accelerate the journey from discovery to real-world impact, ensuring our ideas make a meaningful difference - not just here in Manchester, but nationally and globally. It's an exciting step forward as we continue to push boundaries in research and innovation, and I'm truly looking forward to seeing what she'll achieve.青瓜视频�

Professor Richard Jones, Vice-President, Regional Innovation and Civic Engagement at The University of Manchester, said: 青瓜视频淐atherine青瓜视频檚 leadership comes at a pivotal moment for the Innovation Factory as we seek to amplify Manchester青瓜视频檚 position as an innovation powerhouse for the region and the nation. Her appointment signals our commitment to transforming bold ideas into tangible solutions, fostering a vibrant ecosystem where research fuels regional growth and global breakthroughs. 

"The Innovation Factory, under her guidance, will be a valuable asset to support the University青瓜视频檚 world-class innovators and transformative technologies.青瓜视频�

For more information about the University of Manchester Innovation Factory and its work, please visit www.uominnovationfactory.com.

UoMIF has met or exceeded several key performance targets, reinforcing its commitment to fostering innovation in Manchester and supporting the commercialisation of cutting-edge research to benefit society.

Innovation Factory is The University of Manchester青瓜视频檚 commercialisation arm, dedicated to translating research into commercial opportunities while working closely with academics, industry partners and investors to create and support spinout companies and license cutting-edge technologies.

Over the past year, UoMIF successfully launched seven new spinout companies which span a diverse range of sectors, showcasing the breadth of innovative research emerging from The University of Manchester. These include: Haliogen Power Limited, Plant Organelle Technologies Limited, Oncodrug Limited, VariantValidator Limited, CASA Space Technologies Limited, Kavarney Limited 青瓜视频� with CGSkin recently acquired by Skin Diary Limited as well.

In addition to success in setting up spinouts, UoMIF secured 青瓜视频2.3million in licensing income. Future growth in this space looks positive too, with ongoing negotiations and potential deals progressing.

UoMIF has also secured 青瓜视频9.2million in first investments for new University spinouts, significantly exceeding its target of 青瓜视频5million. This success reflects the growth of investor confidence in high-potential technologies developed within the University.

Commenting on the year-end results, Catherine Headley, CEO of the University of Manchester Innovation Factory, said: "This year青瓜视频檚 performance is a testament to the dedication and hard work of our team and the remarkable talent within The University of Manchester.

青瓜视频淭he successful launch of seven new spinouts and the exceptional level of investment secured are clear indicators that our innovation ecosystem is thriving. While there is room for growth in our licensing income, we are confident that the foundations laid this year will lead to significant future opportunities. We remain committed to supporting our researchers in transforming their groundbreaking ideas into impactful, real-world solutions."

Luke Georghiou, Deputy President and Deputy Vice-Chancellor of The University of Manchester, said: 青瓜视频淭he Innovation Factory plays a crucial role in transforming our academic breakthroughs into tangible societal benefits. The success of this year青瓜视频檚 spinouts and the remarkable level of investment secured are clear evidence of the impact the Innovation Factory is having.

青瓜视频淭hese results demonstrate the University青瓜视频檚 continued commitment to driving technology and entrepreneurship and it highlights the vital place that Manchester has in leading the world青瓜视频檚 innovations. I commend the entire team at UoMIF for their outstanding achievements this year ensuring that The University of Manchester remains at the forefront of research commercialisation.青瓜视频�

This strategic partnership marks a significant milestone for the brands in their pursuit of dermatological research advancement and skincare innovation.  will be launching the first of the CGSkin products, Night Repair Therapy on 25 October 2024. Night Repair Therapy is a true innovation designed to regenerate and rebuild collagen and elastin in prematurely aged skin without irritation.

Founded in 2023 by leading researchers in skin ageing, The Skin Diary is modernising skincare through its innovative product Chapters. The Skin Diary offers prescription-grade skincare routines that leverage skin cycling to deliver optimal outcomes to patients while minimising irritation. 

CGSkin, a University of Manchester spinout, is built on a decade of rigorous research and collaboration between the University and eminent dermatologists Dr Tamara Griffiths and Professor Chris Griffiths. Their suite of anti-ageing products has undergone exhaustive testing to the highest standards, including unprecedented human skin biopsy studies. 

With the acquisition of CGSkin, The Skin Diary is set apart from other skincare brands due to its academic lineage and the expertise of its founders. Professor Chris Griffiths is a distinguished figure in skin research; his seminal research on topical retinoids has made a huge impact on the field of skin ageing. Dr Tamara Griffiths brings invaluable aesthetic science expertise to the partnership.

Only 8.6% of the skincare market is dispensed by physicians, and Chapters provides patients with a fully personalised profile with continuous access to dermatologists through their Skin Diary portal.

Catherine Headley, CEO of the said: 青瓜视频淭his acquisition exemplifies the spirit of innovation, something that is part of the foundation of The University of Manchester.  Impact like this doesn青瓜视频檛 happen overnight; it can be many years in the making. Everyone at the Innovation Factory is proud to see Professor and Dr Griffiths and their research welcomed into The Skin Diary family and we are honoured to have been able to support them on their journey.青瓜视频�

青瓜视频淭he acquisition of CGSkin by The Skin Diary is a testament to our dedication to providing patients with the most effective and innovative skincare solutions,青瓜视频� said Dr Clare Kiely, Chief Medical Officer of the Skin Diary.  青瓜视频淲e are excited to integrate CGSkin青瓜视频檚 ground-breaking products into our portfolio, furthering our mission to empower individuals with access to advanced anti-ageing treatments.青瓜视频�

Skincare is the leading sector in a thriving beauty market, accounting for 40% in .  Growing awareness of physician-dispensed cosmeceuticals means there is increasing demand for prescription-grade skincare options too.

To find out more about The Skin Diary, visit .

The recognition follows on from the publication of the in November 2023, which highlighted the pivotal role UK universities play in driving economic growth and societal impact through the commercialisation of intellectual property developed from university-based research.

The 2023 review outlined recommendations for building a world-leading innovation ecosystem in the UK. In response, The University of Manchester has committed to aligning its spinout practices with these recommendations, reinforcing its dedication to supporting innovation.

Luke Georghiou, Deputy President and Deputy Vice-Chancellor at The University of Manchester, and the institution青瓜视频檚 lead for innovation, said: "The University of Manchester has been and remains committed to fostering innovation and entrepreneurship within our faculties and among our students. By adopting the recommendations from the Independent Review, we are aligning our practices with national goals to create a world-class innovation ecosystem.青瓜视频�

The is the commercialisation arm of The University of Manchester, dedicated to transforming world-class research into commercial ventures that have a positive impact on society.

The Innovation Factory collaborates with academics, industry partners, and investors to develop and support spinout companies, license cutting-edge technologies and drive innovation across various sectors.

The UKRI announcement is available .

Leading investors and universities have come together to launch the USIT Guide which aims to put rocket boosters under the way that the Higher Education sector spins out new companies that take advantage of research breakthroughs.

Many of this country青瓜视频檚 most successful technology firms 青瓜视频� Solexa, Oxford Nanopore, ARM 青瓜视频� started off life as spin-outs from a university, and the publication青瓜视频檚 authors believe many more will now be forthcoming.

This is an area that the UK already excels in. London青瓜视频檚 universities, for example, are more efficient in turning research and development expenditure into spinout companies than many others. They produce a spinout for every 青瓜视频35.35 million invested in research and development compared with 青瓜视频60.42 million, 青瓜视频42.6 million and 青瓜视频54.5 million for Boston, Los Angeles and New York, respectively.

Between them the group behind the new guidance 青瓜视频� which includes venture capitalist firms Abingworth, Sofinnova and Cambridge Investment Capital, and universities Oxford, Imperial and UCL 青瓜视频� has helped set up 376 new companies in the last five years, raising over 青瓜视频8.6 billion in investment.

But the USIT Guide青瓜视频檚 backers believe it can build on this success and allow both universities and venture capitalists to ramp up the whole process of setting up spin-outs by providing direction and advice in such areas as equity share and IP. As it stands, many of these deals are created from scratch, which is both inefficient and sometimes fails to learn the lessons from previous success stories.

The publication, which is supported by TenU, a group of university technology transfer offices in the UK and US, including MIT, Stanford and Columbia, reflects successful practice around the world.

Diarmuid O青瓜视频橞rien, Chief Executive of Cambridge Enterprise and chair of the USIT Guide working group, said: 青瓜视频淭he USIT Guide can unlock the full potential from UK universities research, helping to create more spin-outs faster and attracting increased venture investment. USIT can support our universities create the companies that can contribute to solving the great challenges of our time, from climate to health and the digital revolution.青瓜视频�

Jessica Corner, the Executive Chair of Research England, which funded the initiative, said: 青瓜视频淭he USIT Guide has come out of the deep professionalism and commitment of UK tech transfer offices to collaboration: sharing approaches internationally, and working with others 青瓜视频� particularly investors 青瓜视频� to make our ecosystem more effective.青瓜视频�

Andrew Wilkinson, CEO of the University of Manchester Innovation Factory said: 青瓜视频淭enU provides an invaluable informal platform to understand how national governments, investors and the Universities can collaborate together more effectively to ensure that the fantastic research from our world-leading institutions can create positive social, economic, and environmental impact.  Having members from the UK, the USA and mainland Europe enables us to identify the differences and similarities between the approaches we all take to IP commercialisation and dispel some of the misunderstandings about the way things are done and challenges in different geographies.青瓜视频�

In the past three years, the University of Manchester Innovation Factory has helped UoM academics create 32 IP-rich spinouts (9 in 2019-20, 13 in 20-21, 10 in 21-22) and has generated licensing income of 青瓜视频13.85M from third party non-spinout licensees.  In addition, 青瓜视频9.8M in first-time investment into UoM spinouts has been secured, helping to grow these Manchester-born spinouts.

Research from Manchester and other UK universities promises to be the engine room of the new economy. If universities partner effectively with business and government, these spinouts will generate significant wealth throughout the north of England, creating companies, employing people and raising productivity.

With a team of 44 and drawing on the research and expertise of the University青瓜视频檚 academics and students, the Innovation Factory assesses and scopes research with IP potential and advises startups on critical legal, investment and asset management issues as they scale up.

A copy of The USIT Guide is .

The list is in , Europe青瓜视频檚 influential media monitor of European tech start-ups.  Backed by the Financial Times, Sifted is the leading media brand for the European start-up community.

Two of the top ten highlighted start-ups 青瓜视频� and 青瓜视频� have been created and nurtured within the University of Manchester Innovation Factory (UoMIF).

Sifted says: 青瓜视频淭here青瓜视频檚 a new generation of entrepreneurs taking the European tech scene by storm.  From Madrid to Milan, Bucharest to Berlin, startup innovators are rewriting the economy青瓜视频檚 rules and making waves across the continent. With some 98 cities producing at least one tech unicorn (so far) 青瓜视频� Europe has created a decentralised Silicon Valley.青瓜视频�

Under UoMIF青瓜视频檚 CEO Andrew Wilkinson, the technology transfer organisation has created 32 IP-rich spinout companies in the three years.

Sifted青瓜视频檚 青瓜视频榯op ten university spinouts to watch out for青瓜视频� says: 青瓜视频淲atercycle Technologies is a University of Manchester (UoM) climate tech spinout. The company has patented a filtration process that can extract lithium from sub-surface waters 青瓜视频� which could be huge for the EV space, which needs lithium in huge quantities for making batteries. It青瓜视频檚 also working with Cornish Lithium, which focuses on environmentally responsible lithium extraction.青瓜视频�

 青瓜视频淔OTENIX is another UoM spinout, which uses its IP-protected machine learning and 3D imaging tech to detect diseases and pests and improve harvest quality. Brexit, climate change and the Ukraine war are putting unprecedented pressure on crop yield, and we青瓜视频檙e seeing a growing demand for tech in this space.青瓜视频�

Andrew Wilkinson, CEO of The University of Manchester Innovation Factory said: 青瓜视频淚t青瓜视频檚 great that these two innovative University of Manchester spinout companies have been recognised as being among the very best European tech startups. Both these businesses are led by brilliant young entrepreneurs and have the potential to make an enormous environmental, social and economic impact in their target markets, as well as fantastic returns for their investors.青瓜视频�

, with its mission to enable cleaner water supplies for the world's growing demand, has developed an energy-efficient and highly versatile membrane coating based around a material called modified molybdenum disulphide (MoS₂) to create an innovative water filtration solution.  

The technology comes from research led by  and , at The University of Manchester, working in partnership with innovation experts at the University青瓜视频檚 (GEIC).  

This team has used a two-dimensional version of MoS_2, part of which is a natural crystal with physical properties that are complementary to those of , the world青瓜视频檚 first 2D material, originally isolated at The University of Manchester. 

Molymem and its filtration application has been awarded an investment funding package of 青瓜视频500,400. Among the private sector investors are , Manchester Angels and NorthInvest.

Ray Gibbs, Chairman and Director at Molymem, said this new funding would enable the company to scale up and deliver on its mission. He said: 青瓜视频淣ew 2D materials for membranes are needed to improve sustainability, accessibility and tackle one of the world青瓜视频檚 greatest problems 青瓜视频� delivering clean fresh water for all.青瓜视频�

青瓜视频淭he application of 2D advanced materials into water filtration technologies will, we are confident, help provide solutions to this critical global challenge.青瓜视频�   

Working with businesses and utility companies Molymem has coated a variety of membrane systems and tested the rejection of various salts and other organic molecules, such as nitrates. The performance is equal to or better than existing commercial solutions - but at much lower cost, making the Molymem system a 'greener and cheaper' option.青瓜视频�

Dr Mark Bissett Chief Scientific Officer (Molymem Limited), Reader in Nanomaterials, Dept. of Materials (University of Manchester) commented 青瓜视频淚t青瓜视频檚 incredibly exciting to see our technology, which was developed here in the labs at the University of Manchester as a fundamental research project, be successfully spun out into a company and receiving this funding. Going forward I look forward to seeing our technology have real commercial impact and see our products improving sustainability in multiple industries.青瓜视频�

Richard Lydon, a leading filtration expert and senior advisor to Molymem explained: 青瓜视频淎ccess to clean fresh water is one of the greatest problems we face in the world. Factors that impact on the availability of clean water include climate change, water quality, pollution, and population growth.

青瓜视频淎t the same time, water and wastewater treatment plants across the world need to be upgraded to keep pace with legislation and the ever-growing demand for drinking water. This unique technology is an added value to existing membrane systems reducing particulate 'clogging' of the current filter, enabling improved life, reducing the use of chemicals and increasing flux (water flow). The Molymem platform is robust in any environment and can be tailored (through specific functionalisation of the coating) to reject target particulates such as nitrates, phosphates, PFAS/PFOS, dissolved organics, heavy metals and other pollutants, offering unique selling points to meet the needs of the water industry.青瓜视频�

Rajat Malhotra, Managing Partner, Wren Capital and a member of Cambridge Angels commented, 青瓜视频� We liked the sustainability aspect of Molymem and the strong management to apply novel technology into a significant market in need of new membranes to deal with the increasing threat of particulate pollution (especially nitrates) in the water course. We, therefore, wanted to lead a SEED funding round on behalf of Cambridge Angels who were subsequently joined by investors from Manchester Angels and NorthInvest. This first tie-up makes a strong strategic link between Manchester and Cambridge to enhance co-syndication between the investor groups and the hope of more to come.青瓜视频�   

David Levine, Principal of Manchester Angels said: "We're very excited to have participated in Molymem's recent raise. Manchester Angels was established specifically to fund early-stage, game-changing technologies and technology businesses and help support levelling-up for the North."

Jordan Dargue, Board Director of NorthInvest said: ''We were so impressed with the Molymem team's expertise and passion.  The technology is innovative and solves a real market problem so I was thrilled to be able to help the company access funding at this crucial stage.  What青瓜视频檚 more, this round of investment for Molymem is a perfect example of how angel networks can collaborate to help Northern entrepreneurs access investment.  I青瓜视频檓 so pleased for Richard and the Molymem team and look forward to seeing what the future holds. 青瓜视频�

Notes to Editor

1) Richard Lydon is a leading figure in the filtration, separation and membrane markets and is providing valuable advice and guide the Molymem team as it embarks on its commercial journey in wider areas of the clean and deep tech market sectors.

 2) Molymem is a University of Manchester spin-out and has developed and patented a new class of novel nano-coating applied to membranes for ultra-high filtration performance. The 2D functionalised materials can be retrofitted easily to existing membranes, utilising existing infrastructure and a large installed base. The initial focus is in the demand-driven space of clean water, water reuse and species selectivity but with potential across numerous other industry sectors including air, gas cleaning and future clean energy sectors. Chosen routes to market will be via licence and royalty deals with Membrane suppliers, Original Equipment Manufacturers and System Integrators.

3) Cambridge Angels is a leading UK business angel network providing smart capital from entrepreneurs to entrepreneurs. The collaborative Cambridge-based group, actively mentors and invests in innovative teams and their ideas, equipping generations of entrepreneurs to generate returns and help realise their full potential. The group has a strong ethos of backing merit and supporting entrepreneurship. Cambridge Angels members, most of whom are successful entrepreneurs, invest in a wide range of start-up and scale-up businesses with a particular focus on deep-tech, and tools and technologies supporting healthcare.

The study of the patients tested by either PET brain imaging or amyloid deposits in cerebrospinal fluid (CSF) aims to identify a blood test which could help with earlier diagnosis of the disease.

Certain blood biomarkers of amyloid-飦� (Total, A飦�40 and A飦�42), aggregated 伪-synuclein, aggregated Tau (Total and pTAU (181), NFL and DJ-1 have been associated with Alzheimer青瓜视频檚 Disease pathology.

The study is to evaluate the relationship of all these aggregated forms of biomarkers, including oligomers in the blood, to historical PET scan and CSF findings.

Launched this month (October 2022), participants of the study will be aged 50 to 80, who have had an Amyloid PET scan or CSF Amyloid assessment in the last five years that diagnosed the disease.

Dr Farid Khan, CEO at PharmaKure said: 青瓜视频淓very three seconds someone in the world develops dementia. 850,000 in the UK and 44 million worldwide suffer from Alzheimer青瓜视频檚 or dementia related illnesses and this takes a terrible toll on patients and their families.

青瓜视频淭he current annual societal and economic cost of dementia is estimated as$1 trillion, an amount that is expected to double by 2030 unless we find a way to slow the disease.

青瓜视频淥ur hope is this study may lead to a blood test which could help with earlier diagnosis of this disease.

青瓜视频淭hat could lead to better health outcomes, lower health system costs and improved quality of life of patients by offering treatments earlier.青瓜视频�

Professor Andrew Doig of The University of manchester and co-founder of PharmaKure said: 青瓜视频淏lood tests give further understanding of Alzheimer青瓜视频檚 Disease pathology and an insight into formulating strategies for improving clinical outcomes by selecting future treatments that are tailored to the right patient group.

青瓜视频淚n the progression of Alzheimer青瓜视频檚 Disease, it is not clear whether blood biomarkers are associated with brain imaging scans or amyloid in the CSF.  This study could enable us to learn how to get early warning signs of cognitive decline in blood.青瓜视频�

Alzheimer's disease is a fatal illness that causes progressive decline in memory and other aspects of cognition. It is the most common form of dementia, accounting for 60 to 80 percent of all cases.

In 2020, the total cost of cost of care for people with dementia in the UK was 青瓜视频34.7 billion. Globally, the cost was $360 billion and by 2050 the costs could be a $1 trillion according to Alzheimer青瓜视频檚 Research UK.

In the US alone, there was an increase of 8 million new caregivers from 2015 to 2020.